3. Statistical Analysis and Reporting Tools

3.1. Objective

We will develop an open source, cross-platform rodent statistics toolbox in R (rstr) that will perform statistical inference for neuroimaging measures from both microscopy and MRI using data generated by the methods developed in Aims 1 and 2. This will include novel high-dimensional data from neuronal microstructure, as well as subcortical shape and diffusion imaging. These tools will enable reproducible statistical analysis, report-sharing, and visualization, within and across rodent imaging studies.